Phenylpropanoids and polyketides
Apexbio Technology LLC (E,E)-Bisdemethoxycurcumin 33171-05-0 50mg
(E E)-Bisdemethoxycurcumin (CAS 33171-05-0) is a naturally derived curcuminoid and a structural analog within the demethoxycurcumin class Research demonstrates that this compound modulates multiple inflammatory signaling pathways and alters the expression of various inflammatory mediators It has been shown to induce cell cycle arrest promote apoptosis in cancer cells and inhibit proliferation-related pathways (E E)-Bisdemethoxycurcumin is widely utilized in studies investigating the molecular mechanisms of inflammation tumor cell biology and the pharmacological properties of curcuminoid derivatives
Medchemexpress LLC Myricetin | 529-44-2 | C₁₅H₁₀O₈ | 100 MG
Myricetin is an analytical standard intended for research and analytical applications. This plant-derived flavonoid exhibits strong antioxidant, anticancer, antidiabetic, and anti-inflammatory activities. It is commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Common plant-derived flavonoid
- Strong antioxidant, anticancer, antidiabetic, and anti-inflammatory activities
- Reference standard for research and analytical applications
- Suitable for HPLC, GC, and MS experiments
Cayman Chemical EpIcatechIn Galate 10mg
A natural catechin which inhibits the growth of cancer cells and has anti-inflammatory effects; has potent antioxidant activity and facilitates the killing of methicillin-resistant strains of S. aureus
Medchemexpress LLC Myricetin | 529-44-2 | C15H10O8 | 200 MG
Myricetin is a plant-derived flavonoid known for its strong antioxidant, anticancer, antidiabetic, and anti-inflammatory properties. It exhibits diverse cellular effects, including radical scavenging activity and the ability to modulate various signaling pathways, making it suitable for a wide range of research applications.
- Exhibits scavenging activity against various radicals and ions.
- Prevents cancer cell death by apoptosis through regulation of PI3K/Akt and MAPK signaling pathways.
- Displays antiphotoaging effects by quenching free radicals in the skin and suppressing UVB-induced COX-2 expression.
- Inhibits human Hsp70 with notable IC50 values.
- Causes inhibition of rabbit platelet aggregation induced by ADP, arachidonic acid, collagen, and PAF.
Indofine Chemical Linarin With Hplc, 5 Mg
LINARIN with HPLC, Flavonoid & Coumarins, 480-36-4, 98.5% by HPLC, 5 mg
Medchemexpress LLC (-)-Epigallocatechin-3-O-(4-O-methyl)gallate | 224434-07-5 | MFCD06799453 | 472.40 | 1 MG
(-)-Epigallocatechin-3-O-(4-O-methyl)gallate is an orally active catechin derivative found in Taiwanese oolong tea. It can inhibit histamine release and exhibits anti-inflammation and anti-allergic effect. It can be used for researches of immunology and inflammation, such as type I allergic.
- Inhibits histamine release from IgE/antigen-activated mouse mast cells (45% inhibition rate at 50 μg/mL).
- Exhibits excellent plasma stability (only 10% degradation rate at 500 μg/mL for 15 mins).
- Significantly inhibits type I allergic reactions in mice sensitized with ovalbumin (5-50 mg/kg, i.g.).
- Achieved approximately 50% inhibition rate of abdominal wall blue dye permeation at 10 mg/kg in animal models.
Medchemexpress LLC Doxorubicin (hydrochloride) | 25316-40-9 | C27H30ClNO11 | 25 MG
Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR) is a cytotoxic anthracycline antibiotic and an anti-cancer chemotherapy agent. It functions as a potent human DNA topoisomerase I and topoisomerase II inhibitor, reducing basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Additionally, it induces apoptosis and autophagy.
- Cytotoxic anthracycline antibiotic
- Anti-cancer chemotherapy agent
- Potent human DNA topoisomerase I and II inhibitor
- Reduces basal phosphorylation of AMPK and acetyl-CoA carboxylase
- Induces apoptosis and autophagy
- Suitable for neutral or weakly acidic solvents
- Melting/freezing point of 216°C
- For research use only
Cayman Chemical Hesperetin Natural Products Ex
A flavonoid with diverse biological activities; reduces ApoB protein levels, ACAT2 expression, and LDL degradation in HepG2 cells from 10-200 µM; inhibits IgG-induced β-hexosaminidase release from RBL-2H3 cells (IC50 = 0.099 mg/ml); inhibits LPS-induced NO production and reduces levels of iNOS, IL-6, and IL-1β in BV-2 microglial cells; inhibits passive cutaneous anaphylaxis in mice at 5 mg/kg; reduces body weight loss, colon shortening, and ulcer severity in a mouse model of TNBS-induced ulcerative colitis; reduces cortical and hippocampal neuronal apoptosis and increases time spent in the target quadrant in the Morris water maze in a mouse model of LPS-induced neuronal inflammation
Selleck Chemical LLC Xanthohumol
Xanthohumol a prenylated chalcone from hop inhibits COX-1 and COX-2 activity and shows chemopreventive effects Xanthohumol inhibits diacylglycerol acyltransferase 1 (DGAT1) and DGAT2 with both IC50 of 40 M Xanthohumol is also a potent antiviral agent against a series of DNA and RNA viruses Xanthohumol induces growth inhibition and apoptosis in cancer cells Phase 1
Selleck Chemical LLC Daunorubicin HCl S3035-50mg
Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0 02 M in a cell-free assay Daunorubicin is a topoisomerase II inhibitor that induces apoptosis Daunorubicin (RP 13057) HCl can be used to induce animal models of Kidney Disease
Chem-Impex International, Inc. 7-Hydroxy-4-methylcoumarin | 90-33-5 | MFCD00006866 | 25G
7-Hydroxy-4-methylcoumarin, 90-33-5, MFCD00006866, 25G